How Hormones Work

Review Questions

A new antagonist molecule has been discovered that binds to and blocks plasma membrane receptors. What effect will this antagonist have on testosterone, a steroid hormone?

  1. It will block testosterone from binding to its receptor.
  2. It will block testosterone from activating cAMP signaling.
  3. It will increase testosterone-mediated signaling.
  4. It will not affect testosterone-mediated signaling.

Hint:

D

What effect will a cAMP inhibitor have on a peptide hormone-mediated signaling pathway?

  1. It will prevent the hormone from binding its receptor.
  2. It will prevent activation of a G-protein.
  3. It will prevent activation of adenylate cyclase.
  4. It will prevent activation of protein kinases.

Hint:

D

When insulin binds to its receptor, the complex is endocytosed into the cell. This is an example of ______ in response to hormone signaling.

  1. cAMP activation
  2. generating an intracellular receptor
  3. activation of a hormone response element
  4. receptor down-regulation

Hint:

D