This pathway describes how DNA ligase, a key enzyme in DNA replication, is used in gene cloning to create a recombinant plasmid. This pathway supports ABE lab 3: Building a Recombinant Plasmid.
This pathway explains how restriction enzymes are used in gene cloning to obtain the DNA pieces that will create a recombinant plasmid. This pathway supports ABE labs 2, 2a, 3, 4, and 4a.
This video illustrates how to test guide RNAs to facilitate the cleaving of a macrophage gene in vitro.
Video lesson presents an introduction to what cancer is and how it is the by-product of broken DNA replication. [12:35]
Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.
Meet a chemist who owns his own business that develops synthetic DNA molecules designed to reprogram cells and help cure diseases. Hear the importance of writing, communication skills and creativity to becoming a successful chemist.
Through a narrated presentation learn about the cell theory, and find out about the characteristics all cells share. [6:38]
In this interactive activity adapted from the University of Nebraska, learn how and where transcription and translation occur within a cell and observe both processes in detail.
This pathway explores the processes of transcription and translation that allow cells to produce proteins from DNA.
This video explains how to sort small molecules using a technique called column chromatography.
Paul Nurse describes his research that showed that humans share some genes with organisms as different from us as simple brewer's yeast. Footage from Secret of Life: "Immortal Thread."
Esta vía explica cómo se utilizan las enzimas de restricción en la clonación de genes para obtener las piezas de ADN que crearán un plásmido recombinante. Esta vía es compatible con los laboratorios ABE 2, 2a, 3, 4 y 4a.
In questo video didattico, gli insegnanti delle scuole superiori Anu Deshpande e Aaron Matthieu spiegano cos’è un plasmide e perché è uno strumento utile nella biotecnologia.
Questo video spiega come ordinare le molecole piccole utilizzando una tecnica chiamata cromatografia su colonna.
Este interactivo desplegable demuestra el modo en que las enzimas de
restricción (también denominadas endonucleasas) funcionan y el motivo por el
cual se pueden utilizar como herramientas para analizar el ADN y crear
plásmidos recombinantes.
Learn about deoxyribonucleic acid. Get an overview of DNA bases, complementary base pairing, and the structure of the double helix. [13:02]
Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.
Learn about deoxyribonucleic acid. Get an overview of DNA bases, complementary base pairing, and the structure of the double helix. [13:02]
Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.
Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.
Use this tutorial as an introduction to DNA cloning and recombinant DNA. [11:08]
Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.
Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint") on strips of filter paper and then place one paper strip end in water. As water travels along the paper strips, students observe the pigments that compose the paint decompose into their color components. This is an example of the chromatography concept applied to DNA forensics, with the pigments in the paint that define the color being analogous to DNA fragments of different lengths.
This scrollable interactive takes users on a tour of the DNA double helix, explaining how nucleotide base pairing leads to DNA's unique shape.