Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

By the end of this section, you will be able to do the following:

Describe how changes to gene expression can cause cancer
Explain how changes to gene expression at different levels can disrupt the cell cycle
Discuss how understanding regulation of gene expression can lead to better drug design

By the end of this section, you will be able to do the following:

Describe how cancer is caused by uncontrolled cell growth
Understand how proto-oncogenes are normal cell genes that, when mutated, become oncogenes
Describe how tumor suppressors function
Explain how mutant tumor suppressors cause cancer

By the end of this section, you will be able to do the following:

Describe the structure of prokaryotic and eukaryotic genomes
Distinguish between chromosomes, genes, and traits
Describe the mechanisms of chromosome compaction

By the end of this section, you will be able to do the following:

Describe the three stages of interphase
Discuss the behavior of chromosomes during karyokinesis/mitosis
Explain how the cytoplasmic content is divided during cytokinesis
Define the quiescent G0 phase

The Cell Biology Project at the University of Arizona provides an explanation of mitosis, DNA basics, diagrams and a practice exercise.

This pathway provides an introduction to the cell cycle and how its regulation is important to normal cell division. Cancer is often caused by unregulated cell division. For a deeper look at this topic, we recommend the pathway Cell Reproduction from the OpenStax textbook Biology for AP® Courses.

This multimedia article includes animations, pictures, video, biographical information, and quiz questions that are accessed by clicking on buttons along the bottom of the page. The topic is the study of cell division, mitosis, and cell death.

Drawings and animations, are used to help participants understand the differences between and steps involved in mitosis and meiosis. The cell cycle as well as individual steps of mitosis and meiosis are included in this learning material.