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Bindu Balani in the Xchange: The Epidemiological Link
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An infectious disease specialist at Hackensack University Medical Center in New Jersey, Dr. Bindu Balani treated the state's first confirmed COVID-19 patient in March 2020. In this episode, Bindu shares her experiences on the front line of the battle to identify, treat, and stem the subsequent surge of COVID-19 cases. From this unique vantage point, we learn how all units of the hospital mobilized and adapted to protect and serve the patients in their care. A new virtual interview series from LabXchange at Harvard University, the Xchange showcases the diverse roles, projects, and initiatives that make up the intersecting fields of science, education, and health. Hosted by LabXchange Faculty Director Robert Lue, our first season features a range of perspectives on the impact of COVID-19.

Subject:
Practitioner Support
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
Biomolecules
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Educational Use
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This pathway provides an overview of the four classes of biological molecules (lipids, carbohydrages, proteins and nucleotides) and how they are assembled.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023
Biotechnology
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This pathway introduces how DNA can be manipulated using different molecular tools and techniques. For a deeper look at this topic, we recommend the pathway Biotechnology and Genomics from the OpenStax textbook Biology for AP® Courses.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023
Building a Recombinant Plasmid: DNA Ligase
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This pathway describes how DNA ligase, a key enzyme in DNA replication, is used in gene cloning to create a recombinant plasmid. This pathway supports ABE lab 3: Building a Recombinant Plasmid.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023
Building a Recombinant Plasmid: Restriction Enzymes
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Educational Use
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This pathway explains how restriction enzymes are used in gene cloning to obtain the DNA pieces that will create a recombinant plasmid. This pathway supports ABE labs 2, 2a, 3, 4, and 4a.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023
CRISPR Cas9 Genome Editing with Dr. Richard Sherwood
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Educational Use
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Guest lecture recorded July 28, 2020 with Professor Richard Sherwood, Assistant Professor of Medicine at Brigham and Women’s Hospital. Molecular cloning is essential to research in genetics and cell biology. In this webinar, Dr. Sherwood shares how his lab uses molecular cloning to power their work in genetics and CRISPR/Cas9 genome editing.

Subject:
Biology
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
CRISPR-Cas9 Triggers DNA Repair Mechanisms
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The CRISPR-Cas9 editing tool causes a double-stranded break in target DNA that immediately triggers cellular DNA repair mechanisms to fix this dangerous situation. These repair mechanisms can be taken advantage of by scientists to disrupt or precisely change genes.

Subject:
Biology
Science
Material Type:
Interactive
Provider:
LabXchange
Provider Set:
LabXchange Interactives
Date Added:
11/04/2019
CRISPR-Cas9 in Action: A Real-Time Video
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Educational Use
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This video shows how the Cas9-gRNA complex cleaves DNA visualized in real-time using atomic force microscopy. Astonishingly, single molecules of Cas9 and DNA can be made visible with this technology.

Subject:
Biology
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
CRISPR Workshop with Dr. Jessica Whited
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Guest lecture recorded July 30, 2020 by Dr. Jessica Whited, Assistant Professor of Stem Cell and Regenerative Biology at Harvard University. Dr. Whited studies limb regeneration in axolotl salamanders, with the ultimate goal of discovering how to regenerate limbs in patients. In this webinar, Dr. Whited discusses how her work involves using Cas9-mediated gene drives to generate axolotls with the desired genetic backgrounds.

Subject:
Biology
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
Caroline Levander in the Xchange: Building Resilient Ecosystems for Education
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Educational Use
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In this episode on Building Resilient Ecosystems for Education, Dr. Caroline Levander, who views university campuses as places of passion and dynamism, will provide insight into her roles as a university leader and scholar, and discuss the nuts and bolts of building community in higher education. A new virtual interview series from LabXchange at Harvard University, The Xchange showcases the diverse roles, projects, and initiatives that make up the intersecting fields of science, education, and health. Hosted by LabXchange Faculty Director Robert Lue, our first season features a range of perspectives on the impact of COVID-19.

Subject:
Practitioner Support
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
Cas9-mediated Gene Drives in Axolotls with Dr. Jessica Whited
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Educational Use
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Join us for a talk on CRISPR by Jessica Whited, Assistant Professor of Stem Cell and Regenerative Biology at Harvard University. Dr. Whited studies limb regeneration in axolotl salamanders, with the ultimate goal of discovering how to regenerate limbs in patients. Her work involves using Cas9-mediated gene drives to generate axolotls with the desired genetic backgrounds. Recorded live: July 30th, 1 – 2:30 pm EDT.

Subject:
Biology
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
Case Studies
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Educational Use
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Progress in science comes from sharing ideas and expanding on the work of others. LabXchange helps preserve the research of young scientists through our case study asset, which makes it easy to share and communicate research with others. By constructing a case study, students learn to communicate science in a concise and accessible way and model the formats used by professional scientists.

Subject:
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
Cell Communication
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Educational Use
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This pathway provides an introduction to cellular mechanisms of communication, highlighting one of the primary mechanisms: signal transduction pathways. For a deeper look at this topic, we recommend the pathway Cell Communication from the OpenStax textbook Biology for AP® Courses.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023
Cell Cycle and Cancer
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Educational Use
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This pathway provides an introduction to the cell cycle and how its regulation is important to normal cell division. Cancer is often caused by unregulated cell division. For a deeper look at this topic, we recommend the pathway Cell Reproduction from the OpenStax textbook Biology for AP® Courses.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023