Students learn how engineers apply their understanding of DNA to manipulate specific genes to produce desired traits, and how engineers have used this practice to address current problems facing humanity. They learn what genetic engineering means and examples of its applications, as well as moral and ethical problems related to its implementation. Students fill out a flow chart to list the methods to modify genes to create GMOs and example applications of bacteria, plant and animal GMOs.

This interactive introduces how HIV enters the host cell and uses its resources to
reproduce.

Students perform an activity similar to the childhood “telephone” game in which each communication step represents a biological process related to the passage of DNA from one cell to another. This game tangibly illustrates how DNA mutations can happen over several cell generations and the effects the mutations can have on the proteins that cells need to produce. Next, students use the results from the “telephone” game (normal, substitution, deletion or insertion) to test how the mutation affects the survivability of an organism in the wild. Through simple enactments, students act as “predators” and “eat” (remove) the organism from the environment, demonstrating natural selection based on mutation.

Students learn about mutations to both DNA and chromosomes, and uncontrolled changes to the genetic code. They are introduced to small-scale mutations (substitutions, deletions and insertions) and large-scale mutations (deletion duplications, inversions, insertions, translocations and nondisjunctions). The effects of different mutations are studied as well as environmental factors that may increase the likelihood of mutations. A PowerPoint® presentation and pre/post-assessments are provided.

This site is a must see for any lesson or unit on biotechnology! It is a companion to the PBS video "Bloodlines: Technology Hits Home," although it can certainly be used without the video. It's a fantastic site that will challenge students to think about their opinions in several ethical dilemmas. There is a timeline of genetic and reproductive technology and more.

This interactive will present the rules for designing precise nucleotide sequences
called PCR primers. Designing primers for a PCR reaction is an important step
because the way they bind to the template DNA dictates much of the success of
the PCR reaction.

Watch how NJ high school students apply basic principles of molecular biology to solve real research probloms and publish their own genome research at GenBank, the international genomic sequence database. [6:12]

Your genome, every human's genome, consists of a unique DNA sequence of A's, T's, C's and G's that tell your cells how to operate. Thanks to technological advances, scientists are now able to know the sequence of letters that makes up an individual genome relatively quickly and inexpensively. This learning module takes an in-depth look at the science behind the sequence. [5:05]

This video segment from NOVA: "Cracking the Code of Life" examines the social and ethical implications of genome research. [4 min, 8 sec]

Sourdough experiment: grow wild yeast and bacteria to make your own sourdough bread