Material Type:
Module
Provider:
Rice University
Tags:
Anaphase, Binary Fission, Cancer, Cdk, Cell Cycle, Cell Cycle Checkpoint, Cell Cycle Control, Cell Cycle Regulation, Cell Division, Cell Motion, Cell Plate, Cell Reproduction, Centriole, Centromere, Checkpoint, Chromatid, Chromosome, Chromosome Compaction, Cleavage Furrow, Condensin, Cyclin, Cyclin-dependent Kinase, Cytokinesis, Cytoplasm, DNA, Diploid, Double Helix, Eukaryotic Genome, First Gap, FtsZ, G0 Phase, G1, G1 Checkpoint, G1 Phase, G2, G2 Checkpoint, G2 Phase, Gamete, Gene, Genome, Genomic DNA, Golgi Apparatus, Haploid, Histone, Histone Protein, Homologous Chromosome, Inhibition of Cell Division, Initiation of Cell Division, Interphase, Karyokinesis, Kinetochore, Locus, M Checkpoint, Metaphase, Metaphase Plate, Mitosis, Mitotic Phase, Mitotic Spindle, Mutation, Negative Regulation, Nucleosome, Oncogene, Origin, P21, P53, Prokaryotic Cell Division, Prokaryotic Genome, Prometaphase, Prophase, Proto-oncogene, Quiescent, Rb, Retinoblastoma Protein, S Phase, Second Gap, Septum, Sister Chromatid, Somatic Cell, Spindle Checkpoint, Telophase, Trait, Tumor Suppressor, Tumor Suppressor Gene
Language:
English

Introduction

Image A shows two conjoined cells forming a dumbbell shape; the fertilization envelope has been removed so that the mesh-like outer layer can be seen. Image B shows the sea urchin embryo when it has divided into 16 conjoined cells; the overall shape is rounder than in image A. Image C shows a “water melon” sea urchin which appears as a peach-colored ball covered in white protruding spines.
A sea urchin begins life as a single diploid cell (zygote) that (a) divides through cell division to form two genetically identical daughter cells, visible here through scanning electron microscopy (SEM). After four rounds of cell division, (b) there are 16 cells, as seen in this SEM image. After many rounds of cell division, the individual develops into a complex, multicellular organism, as seen in this (c) mature sea urchin. (credit a: modification of work by Evelyn Spiegel, Louisa Howard; credit b: modification of work by Evelyn Spiegel, Louisa Howard; credit c: modification of work by Marco Busdraghi; scale-bar data from Matt Russell)

A human, like every sexually reproducing organism, begins life as a fertilized egg (embryo) or zygote. In our species, billions of cell divisions subsequently must occur in a controlled manner in order to produce a complex, multicellular human comprising trillions of cells. Thus, the original single-celled zygote is literally the ancestor of all cells in the body. However, once a human is fully grown, cell reproduction is still necessary to repair and regenerate tissues, and sometimes to increase our size! In fact, all multicellular organisms use cell division for growth and the maintenance and repair of cells and tissues. Cell division is closely regulated, and the occasional failure of this regulation can have life-threatening consequences. Single-celled organisms may also use cell division as their method of reproduction.