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How Do Restriction Enzymes Cut Plasmids?
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This scrollable interactive demonstrates how restriction enzymes (also called endonucleases) work and why they can be used as tools to analyze DNA and create recombinant plasmids.

Subject:
Biology
Science
Material Type:
Interactive
Provider:
LabXchange
Provider Set:
LabXchange Interactives
Date Added:
09/10/2019
Human Biology - Genetics (Student's Edition)
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CC BY-NC-SA
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The Genetics Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Subject:
Biology
Science
Material Type:
Activity/Lab
Textbook
Provider:
CK-12 Foundation
Provider Set:
CK-12 FlexBook
Author:
Program in Human Biology, Stanford University
Date Added:
02/04/2011
Human Biology - Lives of Cells (Student's Edition)
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CC BY-NC-SA
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The Lives of Cells Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Subject:
Biology
Science
Material Type:
Activity/Lab
Textbook
Provider:
CK-12 Foundation
Provider Set:
CK-12 FlexBook
Author:
Program in Human Biology, Stanford University
Date Added:
02/04/2011
Imaging DNA Structure
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Students are introduced to the latest imaging methods used to visualize molecular structures and the method of electrophoresis that is used to identify and compare genetic code (DNA). Students should already have basic knowledge of genetics, DNA (DNA structure, nucleotide bases), proteins and enzymes. The lesson begins with a discussion to motivate the need for imaging techniques and DNA analysis, which prepares students to participate in the associated two-part activity: 1) students each choose an imaging method to research (from a provided list of molecular imaging methods), 2) they research basic information about electrophoresis.

Subject:
Engineering
Life Science
Science
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Inside the DNA
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Students conduct their own research to discover and understand the methods designed by engineers and used by scientists to analyze or validate the molecular structure of DNA, proteins and enzymes, as well as basic information about gel electrophoresis and DNA identification. In this computer-based activity, students investigate particular molecular imaging technologies, such as x-ray, atomic force microscopy, transmission electron microscopy, and create short PowerPoint presentations that address key points. The presentations include their own explanations of the difference between molecular imaging and gel electrophoresis.

Subject:
Engineering
Life Science
Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Introduction to Genetic Engineering and Its Applications
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Students learn how engineers apply their understanding of DNA to manipulate specific genes to produce desired traits, and how engineers have used this practice to address current problems facing humanity. They learn what genetic engineering means and examples of its applications, as well as moral and ethical problems related to its implementation. Students fill out a flow chart to list the methods to modify genes to create GMOs and example applications of bacteria, plant and animal GMOs.

Subject:
Engineering
Life Science
Science
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014
The King of Dinosaurs or a Chicken Dinner?
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Could a Tyrannosaurus be created in a modern-day lab? Join paleontologist, Jack Horner, in using protein sequencing to find the closest relative to the T-Rex, and then hypothetically re-creating a specimen in the lab.

Subject:
Mathematics
Science
Material Type:
Audio/Video
Provider:
Massachusetts Institute of Technology
Provider Set:
Blossoms
Date Added:
10/03/2023
Life's Instruction Manual: Interactive Lesson: UNC-TV Science
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Educational Use
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The human genome serves as an instruction manual for life, with its own distinct letters, alphabet, sentences and chapters. Learn about the genome, nucleotides, DNA and genes with this interactive lesson.

Subject:
Mathematics
Science
Material Type:
Interactive
Lesson
Provider:
PBS LearningMedia
Date Added:
11/06/2023
Ligating DNA Fragments
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This simulation provides the opportunity to practice performing a ligation
reaction in a virtual lab setting. This process uses the enzyme DNA ligase
to attach two DNA fragments using complementary blunt or sticky ends
generated from a restriction enzyme digest.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Simulations
Date Added:
10/25/2023
Ligação de fragmentos de DNA
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Esta simulação proporciona a oportunidade de praticar uma reação de ligação em um cenário de laboratório virtual. Este processo usa a enzima DNA ligase para ligar dois fragmentos de DNA usando extremidades cegas ou coesivas complementares geradas a partir da digestão de uma enzima de restrição.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Simulations
Date Added:
10/25/2023
Ligieren von DNA-Fragmenten
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Diese Simulation bietet die Möglichkeit, die Durchführung einer Ligationsreaktion in einer virtuellen Laborumgebung zu üben. Bei diesem Prozess wird das Enzym DNA-Ligase verwendet, um zwei DNA-Fragmente mit komplementären stumpfen oder kohäsiven Enden, die aus einem Restriktionsenzymverdau stammen, zu verbinden.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Simulations
Date Added:
10/25/2023
Macromolecules
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This pathway provides an overview of biological macromolecules and their properties. The resources in this pathway can be used to introduce or review the structure and function of lipids, carbohydrates, proteins, and nucleic acids. For a deeper look at this topic, we recommend the pathway Biological Macromolecules from the OpenStax textbook Biology for AP® Courses.

Subject:
Biology
Science
Material Type:
Unit of Study
Provider:
LabXchange
Provider Set:
LabXchange Pathways
Date Added:
10/25/2023
Macromolecules: Nucleic Acids: DNA
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CC BY-NC-SA
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A video discussing the molecular structure of DNA. Understand that DNA is made up of a phosphate, deoxyribose sugar, and one of the four nitrogen base. Video also explains how the nitrogen bases pair up to form the double helix structure. Also learn how DNA stores the genetic information for organisms. [13:01]

Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.

Subject:
Science
Material Type:
Audio/Video
Lesson
Provider:
Khan Academy
Date Added:
11/14/2023
Making It Personal: Using DNA to Tailor Cancer Treatments
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Students learn about the growth of cancer through an analogy of a kitchen with an appliance running out of control. Together, student learners investigate case studies of three patients with lung cancer and determine the cell mutation which exists in each case.

Subject:
Science
Material Type:
Audio/Video
Provider:
Massachusetts Institute of Technology
Provider Set:
Blossoms
Date Added:
08/01/2022
Malnutrition, DNA Replication, Development, and Schizophrenia Homework Problem
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CC BY-NC-SA
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At the beginning of a DNA, DNA replication, and mitosis unit, students are given a short science news article summarizing a recent research paper. This assignment links the article to figures and key techniques from a related journal article, requiring students to apply and transfer the knowledge they gained in the unit.

Subject:
Life Science
Science
Material Type:
Activity/Lab
Homework/Assignment
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Pedagogy in Action
Author:
Debby Walser-Kuntz
Sarah Deel
Susan Singer
Date Added:
02/24/2021
Matthew Meselson in the Xchange: The Most Beautiful Experiment in Biology
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Matt Meselson takes us on a journey through his long and storied career, including 60 years as a Harvard biology professor. From memories of his earliest science experiments as a small child to his non-traditional learning path, which included service learning during WWII, to musings on the spirit of cooperation in managing a pandemic and the future of biology and humanity, this episode gives us an insight into a legendary figure in biology. A new virtual interview series from LabXchange at Harvard University, the Xchange showcases the diverse roles, projects, and initiatives that make up the intersecting fields of science, education, and health. Hosted by LabXchange Faculty Director Robert Lue, our first season features a range of perspectives on the impact of COVID-19. View this video (and more like it) on LabXchange: https://www.labxchange.org/

Subject:
Practitioner Support
Science
Material Type:
Lecture
Provider:
LabXchange
Provider Set:
LabXchange Videos
Date Added:
10/25/2023
Maurice Wilkins - Nobel Lecture
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Download and read Maurice Wilkins Nobel Lecture "The molecular configuration of nucleic acids." This lecture, originally given December 11, 1961, is available in pdf format.

Subject:
Science
Material Type:
Primary Source
Provider:
The Nobel Prize
Date Added:
10/03/2023