Students compare and contrast passive and active transport by playing a game to model this phenomenon. Movement through cell membranes is also modeled, as well as the structure and movement typical of the fluid mosaic model of the cell membrane. Concentration gradient, sizes, shapes and polarity of molecules determine the method of movement through cell membranes. This activity is associated with the Test your Mettle phase of the legacy cycle.

Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

By the end of this section, you will be able to do the following:

Explain why and how passive transport occurs
Understand the osmosis and diffusion processes
Define tonicity and its relevance to passive transport

A narrated, video tutorial illustrating how diffusion works. It shows the concentration gradient that diffusion follows, explains the difference between diffusion and facilitated diffusion, and presents real life examples. [7:46]

This pathway introduces the structure of cell membranes and how they function in cellular transport.

This pathway provides an introduction to cellular mechanisms of transport, including a comparison of passive and active mechanisms. For a deeper look at this topic, we recommend the pathway Structure and Function of Plasma Membranes from the OpenStax textbook Biology for AP® Courses.

Movement of ions in and out of cells is crucial to maintaining homeostasis within the body and ensuring that biological functions run properly. The natural movement of molecules due to collisions is called diffusion. Several factors affect diffusion rate: concentration, surface area, and molecular pumps. This activity demonstrates diffusion, osmosis, and active transport through 12 interactive models.

A video presentation describing how transport proteins in the cell membrane allow solutes to cross the cell membrane without the use of cellular energy. [5:41]

Using ordinary household materials, student “biomedical engineering” teams design prototype models that demonstrate semipermeability under the hypothetical scenario that they are creating a teaching tool for medical students. Working within material constraints, each model consists of two layers of a medium separated by material acting as the membrane. The competing groups must each demonstrate how water (or another substance) passes through the first layer of the medium, through the membrane, and into the second layer of the medium. After a few test/evaluate/redesign cycles, teams present their best prototypes to the rest of the class. Then student teams collaborate as a class to create one optimal design that reflects what they learned from the group design successes and failures. A pre/post-quiz, worksheet and rubric are provided.

Through two lessons and five activities, students explore the structure and function of cell membranes. Specific transport functions, including active and passive transport, are presented. In the legacy cycle tradition, students are motivated with a Grand Challenge question. As they study the ingress and egress of particles through membranes, students learn about quantum dots and biotechnology through the concept of intracellular engineering.

A website giving an explanation to the process of osmosis with a PowerPoint presentation, a video of a lab, and a video of an answer to a review question. The PowerPoint presentation reviews the process by which water diffuses through a semi-permeable membrane. Also included on site is video showing a gummy bear lab that illustrates osmosis. Lab places a gummy bear in a bowl of water overnight to see that water moves into the gummy bear. [2:24] The review question poses the issue of why living off salt water could be hazardous to a person's health. [1:47]

Students learn that engineers develop different polymers to serve various functions and are introduced to selectively permeable membranes. In a warm-up activity, they construct models of selectively permeable membranes using common household materials, and are reminded about simple diffusion and passive transport. In the main activity, student pairs test and compare the selective permeability of everyday polymer materials engineered for food storage (including plastic grocery bags, zipper sandwich bags, and plastic wrap) with various in-solution molecules (iodine, corn starch, food coloring, marker dye), assess how the polymer’s permeability relates to its function/purpose, and compare that to the permeability of dialysis tubing (which simulates a cell membrane).