Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

By the end of this section, you will be able to do the following:

Name and describe lung volumes and capacities
Understand how gas pressure influences how gases move into and out of the body

By the end of this section, you will be able to do the following:

Describe how oxygen is bound to hemoglobin and transported to body tissues
Explain how carbon dioxide is transported from body tissues to the lungs

This 15-minute video lesson examines hemoglobin and its role in the circulatory system. [Biology playlist: Lesson 40 of 71].

Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.

This 16-minute video looks at oxygen uptake by hemoglobin in red blood cells. [Biology playlist: Lesson 38 of 71].

Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.

A brief overview of Sickle cell anemia, a genetic disease that affects hemoglobin in the blood. [1:30]

Although mom controls the oxygen source, the fetus has a couple of clever tricks to get the most oxygen possible! Rishi is a pediatric infectious disease physician and works at Khan Academy.

Khan Academy learning modules include a Community space where users can ask questions and seek help from community members. Educators should consult with their Technology administrators to determine the use of Khan Academy learning modules in their classroom. Please review materials from external sites before sharing with students.

This lesson describes how the circulatory system works, including the heart, blood vessels and blood. Students learn about the chambers and valves of the heart, the difference between veins and arteries, and the different components of blood. This lesson also covers the technology engineers have developed to repair the heart if it is damaged. Students also understand how the circulatory system is affected during spaceflight (e.g., astronauts lose muscle in their heart during space travel).

Students randomly select jelly beans (or other candy) that represent genes for several human traits such as tongue-rolling ability and eye color. Then, working in pairs (preferably of mixed gender), students randomly choose new pairs of jelly beans from those corresponding to their own genotypes. The new pairs are placed on toothpicks to represent the chromosomes of the couple's offspring. Finally, students compare genotypes and phenotypes of parents and offspring for all the "couples" in the class. In particular, they look to see if there are cases where parents and offspring share the exact same genotype and/or phenotype, and consider how the results would differ if they repeated the simulation using more than four traits.

This interactive image of an oxygen-binding curve for hemoglobin demonstrates
how changes in the concentration of carbon dioxide impact the environmental
pH and the structure of the hemoglobin protein, thereby altering its ability to
bind oxygen.

This video segment describes the role of the sickle cell gene in natural selection. Footage courtesy of the PBS series Secret of Life: "Accidents of Creation." [4:49]

In this scrollable interactive, the four levels of protein folding are explored in detail by exploring the structure of hemoglobin.

A narrated lesson examining the structure, function, and production of new red blood cells. [5:20]

This scrollable interactive explores the different roles that proteins can play in the cell. Categories of proteins covered include transmembrane proteins, proteins that make up molecular machines like cilia and ribosomes, and enzymes. The four levels of protein structure are also discussed.

This site from WebMD provides an extremely detailed description of a complete blood count, how it is taken, what it measures, and what the results tell you. Links to important terms within the text and a chart that shows average amounts expected during testing are also given.

In a class discussion format, the teacher presents background information about basic human genetics. The number of chromosomes in both body cells and egg and sperm cells is covered, as well as the concept of dominant and recessive alleles. Students determine whether or not they possess the dominant allele for the tongue-rolling gene as an example.